Drugs/Recall·openFDA/drug

Baxter Healthcare Corporation — Class II: CARDENE IV (Nicardipine Hydrochloride) in 0.83% Sodium Chloride Injection, 40 mg in 200 mL

MediumPublished Sep 9, 2026· AI-analyzed Sep 14, 2026View original FDA source
AI-generated regulatory interpretation. The four sections below are an analyst-style summary produced by an AI model from the original FDA source. Always verify against the source before any regulatory, clinical, or commercial decision.
What happened

Baxter Healthcare Corporation has initiated a Class II recall for Cardene IV (Nicardipine Hydrochloride) in 0.83% Sodium Chloride Injection, 40 mg in 200 mL, due to CGMP deviations. The recall remains ongoing and affects products distributed in GALAXY Single-Dose Containers (NDC 43066-016-10).

Who it affects

This recall affects Baxter Healthcare Corporation and healthcare facilities utilizing Cardene IV GALAXY containers, as well as personnel in quality assurance, sterile manufacturing, and hospital procurement.

Why it matters

A Class II designation suggests that exposure to the non-compliant product may cause temporary or medically reversible adverse health consequences, though the source does not specify the exact nature of the CGMP deviation. Regulatory teams should interpret this as a potential failure in sterile manufacturing standards or documentation controls at the Deerfield-linked facility. The 'ongoing' status implies that reconciliation and root cause analysis may still be in progress.

Practical takeaway

QA and Supply Chain teams should immediately verify if affected NDC 43066-016-10 lots are in inventory. Manufacturing teams should investigate if the cited CGMP deviations stem from specific GALAXY container fill-finish processes or broader systemic facility issues.

FDA source material

Class II. Reason: CGMP Deviations. Product: CARDENE IV (Nicardipine Hydrochloride) in 0.83% Sodium Chloride Injection, 40 mg in 200 mL (0.2 mg/mL) in GALAXY Single-Dose Container, Manufactured and Marketed by: Baxter Healthcare Corporation, Deerfield, IL 60015 USA, NDC 43066-016-10.. Firm: Baxter Healthcare Corporation (Deerfield IL United States). Status: Ongoing.

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